H.V.M.N.
™
Yawn

Rejuvenating Sleep Aid.

SleepMoodStress

Yawn is a non-habit-forming sleep aid to support every facet of healthy sleep, so every night can be your best night’s sleep. It can help you fall asleep easier, improve sleep quality and wake up feeling refreshed. Sufficient, high-quality sleep is scientifically agreed upon to be the one of the most important pillars to optimizing cognition and physical performance in the near-term.

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Rejuvenate the brain and body with quality sleep.

Invigorated performance during the day starts with efficient sleep.

Yawn combines the sleep-inducing effects of melatonin and L-Glycine, to help get the body and brain in recharge mode.

Reduce Time to Fall Asleep

Reduced by

7 minstatArrowDownCreated with Sketch.

In 19 studies of melatonin, participants fell asleep 7.06 minutes faster on average.1,2,3

Sleep Well

Increase of

3%Icons/Arrow/RedCreated with Sketch.

Clinical studies on melatonin demonstrated an overall 3% improvement in sleep efficiency.1

YAWN pill image

Ingredients

Magnesium Glycinate

250 mg

Magnesium is an essential dietary mineral, and the second most prevalent electrolyte in the human body

Magnesium deficiency is common in the United States, with an estimated 68% of the population not meeting the FDA recommended daily intake of magnesium3,4,5

The glycinate form adds bioavailability of magnesium and additional glycine content6

H3

Supplementing as magnesium glycinate increases the bioavailability of magnesium and provides additional glycine7

H3

Magnesium is linked to reduced markers of inflammatory stress and improved sleep quality5,8

L-Glycine

500 mg

Amino acid and a neurotransmitter

H3

Improves subjective sensation of sleep quality and mood on waking3,9

H3

Reduces time to fall asleep10

H3

Improved cognitive performance the next day11

L-Theanine

100 mg

Amino acid commonly found in tea12

H4

Reduces stress and anxiety13,14,15,16

H4

Shown to reverse the blood pressure and constriction of brain vessels caused by caffeine intake17,18

Melatonin

1 mg

Hormone produced in the brain that promotes sleep and regulates circadian rhythm (sleep-wake cycle)19

1 mg of melatonin not habit-forming20,21

H4

Reduces the time to fall asleep and improves sleep quality1,2

H4

Helps to normalise the sleep-wake cycle after travel across time zones22

H2

Neuroprotective due to antioxidant and antiinflammatory properties23

H.V.M.N. Evidence Grading

Rooted in principles of science and engineering, we share full knowledge of H.V.M.N. products and their ingredients. Each products is systematically graded by the breadth of evidence available:

H1

Theoretical effect or in vitro evidence

H2

Animal model evidence of effects

H3

Early human evidence of ingredient effects

H4

High-quality human evidence of ingredient effects

H5

Human study of product as sold

Sleep is essential to overall health. A better tomorrow started last night.

Yawn can help improve sleep and enhance cognition the day after a restful night of sleep

Improved Sleep Quality

Ingesting glycine before sleep significantly improved objective sleep quality3. When given glycine before bed, participants of a sleep study showed 50% reduction in subjective fatigue as well as improved "fatigue", "peppiness" and "clear headedness".11

Decrease Stress to Improve Sleep

Magnesium has been linked to reduced markers of stress and improved sleep quality.5,8

Supplement Facts

Serving Size: 1 Capsule
Servings Per Container: 30 (one month supply)
Amount/Serving
% Daily Value
Magnesium Glycinate 250 mg
†
L-Glycine 500 mg
†
L-Theanine 100 mg
†
Melatonin 1 mg
†

† Daily value not established

Other Ingredients: Hypromellose (Vegetable capsule shell), Silicon Dioxide, Magnesium Stearate.

Instructions

Take one capsule of Yawn with a glass of water, one hour before sleeping.

Yawn is designed to be taken as needed, but can be taken on a consistent, nightly basis.

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Scientific Citations

1. Brzezinski, A., Vangel, M. G., Wurtman, R. J., Norrie, G., Zhdanova, I., Ben-Shushan, A., & Ford, I. (2005). Effects of exogenous melatonin on sleep: a meta-analysis. Sleep Med Rev, 9(1), 41-50.
2. Ferracioli-Oda, E., Qawasmi, A., & Bloch, M. H. (2013). Meta-Analysis: Melatonin for the Treatment of Primary Sleep Disorders. PLoS One, 8(5), e63773. doi:10.1371/journal.pone.0063773
3. Inagawa, K., Hiraoka, T., Kohda, T., Yamadera, W., & Takahashi, M. (2006). Subjective effects of glycine ingestion before bedtime on sleep quality. Sleep and Biological Rhythms, 4(1), 75-77. doi:10.1111/j.1479-8425.2006.00193.x
4. Murck, H., & Steiger, A. (1998). Mg2+ reduces ACTH secretion and enhances spindle power without changing delta power during sleep in men -- possible therapeutic implications. Psychopharmacology (Berl), 137(3), 247-252.
5. Nielsen, F. H., Johnson, L. K., & Zeng, H. (2010). Magnesium supplementation improves indicators of low magnesium status and inflammatory stress in adults older than 51 years with poor quality sleep. Magnes Res, 23(4), 158-168. doi:10.1684/mrh.2010.0220
6. Deng, X., Song, Y., Manson, J. E., Signorello, L. B., Zhang, S. M., Shrubsole, M. J., . . . Dai, Q. (2013). Magnesium, vitamin D status and mortality: results from US National Health and Nutrition Examination Survey (NHANES) 2001 to 2006 and NHANES III. BMC Med, 11(1), 187. doi:10.1186/1741-7015-11-187
7. Schuette SA, Lashner BA, Janghorbani M. Bioavailability of magnesium diglycinate vs magnesium oxide in patients with ileal resection. JPEN. Journal of parenteral and enteral nutrition. ; 18(5):430-5.
8. Held K, Antonijevic I. A., Künzel H., Uhr M., Wetter T. C., Golly I. C., Steiger A., Murck H. Oral Mg(2+) supplementation reverses age-related neuroendocrine and sleep EEG changes in humans. Pharmacopsychiatry. 2002 Jul. 35(4), 135-43.
9. Yamadera, W., Inagawa, K., Chiba, S., Bannai, M., Takahashi, M., & Nakayama, K. (2007). Glycine ingestion improves subjective sleep quality in human volunteers, correlating with polysomnographic changes. Sleep and Biological Rhythms, 5(2), 126-131. doi:10.1111/j.1479-8425.2007.00262.x
10. Kunz, D., Mahlberg, R., Müller, C., Tilmann, A., & Bes, F. (2004). Melatonin in patients with reduced REM sleep duration: two randomized controlled trials. The Journal of Clinical Endocrinology & Metabolism, 89(1), 128-134.
11. Bannai, M., Kawai, N., Ono, K., Nakahara, K., & Murakami, N. (2012). The Effects of Glycine on Subjective Daytime Performance in Partially Sleep-Restricted Healthy Volunteers. Front Neurol, 3, 61. doi:10.3389/fneur.2012.00061
12. Borzelleca, J. F., Peters, D., & Hall, W. (2006). A 13-week dietary toxicity and toxicokinetic study with l-theanine in rats. Food Chem Toxicol, 44(7), 1158-1166. doi:10.1016/j.fct.2006.03.014
13. Kimura, K., Ozeki, M., Juneja, L. R., & Ohira, H. (2007). L-Theanine reduces psychological and physiological stress responses. Biol Psychol, 74(1), 39-45. doi:10.1016/j.biopsycho.2006.06.006
14. Tian, X., Sun, L., Gou, L., Ling, X., Feng, Y., Wang, L., . . . Liu, Y. (2013). Protective effect of l-theanine on chronic restraint stress-induced cognitive impairments in mice. Brain Res, 1503, 24-32. doi:10.1016/j.brainres.2013.01.048
15. Unno, K., Fujitani, K., Takamori, N., Takabayashi, F., Maeda, K., Miyazaki, H., . . . Hoshino, M. (2011). Theanine intake improves the shortened lifespan, cognitive dysfunction and behavioural depression that are induced by chronic psychosocial stress in mice. Free Radic Res, 45(8), 966-974. doi:10.3109/10715762.2011.566869
16. Unno, K., Tanida, N., Ishii, N., Yamamoto, H., Iguchi, K., Hoshino, M., . . . Yamada, H. (2013). Anti-stress effect of theanine on students during pharmacy practice: positive correlation among salivary alpha-amylase activity, trait anxiety and subjective stress. Pharmacol Biochem Behav, 111, 128-135. doi:10.1016/j.pbb.2013.09.004
17. Dodd, F. L., Kennedy, D. O., Riby, L. M., & Haskell-Ramsay, C. F. (2015a). A double-blind, placebo-controlled study evaluating the effects of caffeine and L-theanine both alone and in combination on cerebral blood flow, cognition and mood. Psychopharmacology (Berl), 232(14), 2563-2576. doi:10.1007/s00213-015-3895-0
18. Rogers, P. J., Smith, J. E., Heatherley, S. V., & Pleydell-Pearce, C. W. (2008). Time for tea: mood, blood pressure and cognitive performance effects of caffeine and theanine administered alone and together. Psychopharmacology (Berl), 195(4), 569-577. doi:10.1007/s00213-007-0938-1
19. Tuli, H. S., Kashyap, D., Sharma, A. K., & Sandhu, S. S. (2015). Molecular aspects of melatonin (MLT)-mediated therapeutic effects. Life Sci, 135, 147-157. doi:10.1016/j.lfs.2015.06.004
20. Lemoine P., Nir T., Laudon M., Zisapel N. Prolonged-release melatonin improves sleep quality and morning alertness in insomnia patients aged 55 years and older and has no withdrawal effects. J Sleep Res. 2007 Dec. 16(4), 372-80.
21. Zhdanova I. V., Wurtman R. J., Lynch H. J, et al. Sleep‐inducing effects of low doses of melatonin ingested in the evening. Clinical Pharmacology & Therapeutics (1995) 57, 552–558.
22. Herxheimer, A., & Petrie, K. J. (2002). Melatonin for the prevention and treatment of jet lag. Cochrane Database Syst Rev(2), Cd001520. doi:10.1002/14651858.cd001520
23. Koh PO. Melatonin prevents ischemic brain injury through activation of the mTOR/p70S6 kinase signaling pathway. Neuroscience letters. 2008; 444(1):74-8.
View all 23 citations

These statements have not been evaluated by the FDA. Our products are not intended to diagnose, treat, cure, or prevent any disease.

© 2019 HVMN Inc. All Rights Reserved. H.V.M.N.®, Health Via Modern Nutrition™, Nootrobox®, Rise™, Sprint®, Yawn®, Kado™, and GO Cubes® are registered trademarks of HVMN Inc. ΔG® is a trademark of TΔS® and used under exclusive license by HVMN Inc.

H.V.M.N.
38 Mason St, 3rd Floor, San Francisco, CA 94102
Email us: care@hvmn.com

These statements have not been evaluated by the FDA. Our products are not intended to diagnose, treat, cure, or prevent any disease.

© 2019 HVMN Inc. All Rights Reserved. H.V.M.N.®, Health Via Modern Nutrition™, Nootrobox®, Rise™, Sprint®, Yawn®, Kado™, and GO Cubes® are registered trademarks of HVMN Inc. ΔG® is a trademark of TΔS® and used under exclusive license by HVMN Inc.