Research Club

December 20, 2017
research-club

Research is always advancing, and HVMN is here to keep you up to date on the latest of human enhancement. The latest findings are found on well-established medical resources such as PubMed and Liebert Pub, but are often barred with a membership or a hefty fee.

As a company founded on the principle of putting the hard science out there first, we're glad to summarize some of these cutting-edge research articles for you.

Exogenous ketones: Fuel for metabolism?

The purpose of this study was to investigate the effects of consuming two different ketone supplements on healthy people at rest. The two main types of true exogenous ketones that contain the ketone beta hydroxybutyrate (BHB) are ketone esters and ketone salts. While ketone esters are not yet available to buy, they have been tested in healthy volunteers and athletes and have shown that they raise blood ketones, improve physical performance, and aid in some markers of recovery. In contrast, there is very little published positive data on ketone salts illustrating their effects on humans. 

Bright light therapy for depression?

Many people experience fluctuations in their mood that can be linked to changes in light exposure: called ‘Seasonal Affective Disorder’ (aptly: ‘SAD’). One biohack that can help people suffering from SAD is exposure to a special bright blue light box for about an hour a day. Researchers now believe that light box therapy can be a natural way to help treat other kinds of mood disorders, such as bipolar depression. 

Effect of fasting on insulin action

Due to a societal shift to a more sedentary lifestyle (along with constant food intake) insulin resistance is increasingly becoming a major health issue. This study is the first in humans to show that intermittent fasting increases insulin-mediated glucose uptake rates...meaning elevated insulin sensitivity and improved blood-glucose control. 

Ketone salts and athletic performance


In recent years, there has been an increase of ketone salt supplements promising to bring you into ketosis and improve physical and mental performance. It's important to note that not all ketone supplements are the same...there are salts, oils, and esters (which are the raw form of BHB and not yet commercially available). This study specifically examines ketone salts, which are ketone bodies bound to minerals such as sodium, potassium, or calcium.   It's been shown that ketone esters can improve performance and recovery, which is key for sports such as cycling. Do ketone salts actually boost performance in the same manner? 

Can fasting turn white fat into brown fat?

There are two types of fat in your body: Brown fat and white fat. The brown fat is a type of fat that BURNS energy. The white fat is a type of fat that STORES energy. Can intermittent fasting convert your white fat into brown fat?

Melatonin for blood pressure reduction

Melatonin taken at bedtime can reduce blood pressure and may be useful for the mitigation of nocturnal hypertension.

Can L-Theanine Protect The Brain From Enviromental Toxins?

The world is filled with toxins, some coming from everyday items. There is a strong possibility that exposure to modern environmental toxins can have a negative effect on brain health. Can L-Theanine reduce these negative impacts on our brain?

Ketogenic Diet: The Key for Longevity and Memory?

This HVMN Journal brings you two closely related studies that work together to prove the potential benefits the ketogenic diet has on longevity and memory.

Should I Exercise While I Fast?

One of the most common questions asked by fasters is if they should exercise during a fast. The worry that normal exercise routines will be negatively impacted by adding intermittent fasting is an understandable concern. This study aims to answer that question.

Fats vs. Carbs: A Look at Mortality Rate

This study has been getting a lot of attention in the news because the authors claim that their findings directly contradict the current government sanctioned dietary guidelines recommending a low fat diet.

Can Glycine Protect Against Muscle Loss During a Fast?

One of the big challenges avid fasters run into is maintaining muscle mass during periods of caloric restriction. How can one retain all their hard-earned muscle while not eating a single calorie?

L-Theanine to Help with Chronic Stress?

One of the most serious, yet widely ignored, burdens of society is stress. Psychological, physiological or environmental stressors can result in neuropsychological dysfunction such as Major Depressive Disorder (MDD) with cognitive impairment. Can L-Theanine help with this problem?

Does Fasting Affect Muscle Mass?

Concerned about whether intermittent fasting or time-restricted feeding will adversely affect lean muscle mass retention?

Ketogenic Intervention to Delay Cognitive Decline?

It is increasingly becoming appreciated that the ability of the brain to burn glucose is compromised during diseases such as Alzheimer’s disease. The brain maintains its ability to burn ketones during Alzheimer's disease...could this help to slow down cognitive decline? 

Strategies to Improve Adherence to Dietary Weight Loss Interventions in Research and Real-World Settings

How much truth is there to the old saying "the best diet is the one you can stick to"? Or is there more to weight loss?

BHB for spinal cord injuries?

Find out about a study that used a combination of animal and cell experiments to investigate the effects of ketosis on spinal cord injuries.

β-hydroxybutyrate (BHB) alleviates depressive behaviors in mice

How do changes to our genes affect depression, and what's the role of the ketone body, BHB?

Does fasting help with depression?

Intermittent fasting has been shown to have cognitive and physical benefits, but can this practice also be therapeutic for depression? Researchers recently tested fasting as a way to induce antidepressant effects by utilizing mice. What did 9 hours of fasting do for mice who were in an extremely stressful situation?

Emails worth reading.

Once a week, we'll send you the most compelling research, stories and updates from the world of human enhancement.

HVMN Co-founders Michael Brandt and Geoffrey Woo