EGCG (Epigallocatechin Gallate)

Authored by Robert Chen • 
July 10, 2016
 • 2 min read

Effect of EGCG on Attention

A few studies have evaluated epigallocatechin gallate (EGCG) and its effect on human physiology, and attention as well as other domains of cognition. Some studies have found that tea consumption positively effect attention, although it is not clear how much EGCG contributes to the effect.

A study of 27 healthy individuals showed that while epigallocatechin gallate had various physiological effects, there were no significant differences on cognitive performance.

A double-blind, placebo controlled crossover study showed that there were positive effects on brain physiology when EEGs were taken 120 minutes after administration of 300 mg EGCG, compared to placebo. Specifically, there was an "overall increase in alpha, beta and theta activity, also reflected in overall EEG activity, more dominant in midline frontal and central regions, specifically in the frontal gyrus and medial frontal gyrus". Activation in these brain areas, along with the subjects' self-reported reduction in stress, suggest that ECGC modulates attention.

While initial findings of the effects of EGCG on attention are promising, more rigorous scientific research would help to strengthen the use case of EGCG.

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