One axis on which we can study personality is on a scale ranging from neuroticism to positivity.
Neuroticism refers to a tendency to experience negative emotions. Perhaps you may know some people who are anxious, or who have difficulty rebounding from failure or sad events, or people who break down when stressed. These are all characteristics of neuroticism. Neurotic people might change their mood a lot, get irritated or upset easily, or get disturbed by minor things.
Positivity refers to a tendency to experience positive emotions. Perhaps you may know people that are always “chill”, or people who feel happy and relaxed all the time.
Various large scale genetic studies such as genome-wide association studies have identified a number of genetic variants that may influence neuroticism in humans. These genetic variants encode proteins ranging from cell adhesion proteins to neuronal growth factors. (Learn more)
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